The Marian Scott Moffett Papers are divided into three series, which are personal materials, academic and professional materials, and photographs. The personal materials include items of a biographical nature, which provide detail on several periods of her life. The materials begin with her childhood and early education, which focus primarily. Examples include forms of identification, portraits, awards, grade reports, test scores, graduate school admission materials, curricula vitae, correspondence, news clippings, writings, and church leadership materials. This series also includes appointment books, which contain the details of her daily schedule during her years at UT. The fourth series is for flat storage.

The majority of the collection is found in the second series, which deals with her academic and professional career. These items include academic course files, which contain syllabi, notes, student papers and exams. Also, this series includes research materials on architectural education, TVA architecture, church buildings, cantilever barns, planned towns, international research exchange files concerning her study of medieval Polish vernacular architecture, as well as her thesis research notebooks. Also in this series are writings and publications, which includes some of her papers and projects from graduate school, copies of her masters and doctoral theses, architectural education studies, files of correspondence with textbook publishers, files of illustrations for textbooks, permission requests for textbook illustrations, manuscript drafts, published articles. This series contains items concerning her participation at conferences and in professional organizations, particularly the Southeastern Society of Architectural Historians (SESAH). Her personnel files are also in this series, which include annual reports, faculty promotion materials and teaching evaluations. This series also contains files from her time with the School of Architecture, Faculty Senate, Academic Affairs, and other official activities at UT. This includes items dealing with faculty and administration matters, academic program reviews, meeting agendas and minutes, committee materials, budgets, newsletters, and correspondence.

The third series in the collection contains a sizeable amount of photographs, many of them taken by Moffett herself for various architectural research projects, as well as negatives and contact sheets. The photographic topics include cantilever barns, TVA dams, European architecture, and UT colleagues. Some of the pictured locations are East Tennessee, various other places in the United States, England, the Netherlands, France, Spain, Italy, Greece, Austria, Slovakia, Poland, Russia, and the Ukraine. This series also includes files of photographs intended for her textbooks.